ω-Conotoxin-MVIIC - Ion Channels and Transporters
ω-conotoxin MVIIC (omega conotoxin MVIIC) is a conotoxin that has been isolated from the venom of the cone Conus magus. ω-conotoxin MVIIC is a blocker of P/Q (IC50=35 nM) and N-type calcium channels. It inhibits presynaptic Ca2+ channels, including the Ca2+ channels responsible for Ca2+ uptake by rat brain synaptosomes, the P-type Ca2+ channels in cerebellar Purkinje cells, and a significant fraction of ω-conotoxin GVIA-resistant currents in hippocampal CA1 neurons. ω-conotoxin MVIIC also presents an inhibition of ω-conotoxin GVIA-resistant depolarization-induced neurotransmitter release in cerebellar neurons of rats.
Technical specification
 |
Sequence : | H-CKGKGAPCRKTMYDCCSGSCGRRGKC-NH2 (Cys1-Cys16; Cys8-Cys20; Cys15-Cys26) |
 |
MW : | 2749.25 g/mol |
 |
Purity : | > 95% |
 |
Counter-Ion : | TFA Salts |
 |
Delivery format : | Lyophilized |
Price
| Product | Size | Price € | Price $ |
| 08CON002-0.1 mg | 0.1 mg | 132€ | 159$ |
| 08CON002-0.5 mg | 0.5 mg | 330€ | 396$ |
| 08CON002-1 mg | 1 mg | 561€ | 674$ |
If you'd like to learn more about this toxin, visit our product page on our Smartox website—Our sister company specializing in the synthesis of complex toxins.
