Amino acids chart and table reference

Natural peptides and proteins are mainly made of 20 standard amino acids. Many other natural amino acids derivate from these 20 amino acids are also found in the Nature. In addition, amino acid chemistry has allowed to develop thousands of unnatural amino acids to improve peptide properties. Thanks to chemical peptide synthesis procedures, about any kind of amino acids can be incorporated in a peptide sequence contrary to recombinant synthesis.

Discover amino acids properties and contact us for any peptide synthesis requests.

Proteinogenic amino acids chart

Peptides and proteins are mainly made of 20 standard natural amino acids. Amino acids are bound together through amide bonds to form a peptide sequence. Each amino acid has specific properties including hydrophobicity, charge, mass weight, isoelectric point… A combination of these very different building blocks allows to generate an infinity of peptide structures making this ressource very attractive for therapeutic development.

Access SB-PEPTIDE’s solubility guidelines and peptide calculator.

Amino Acids with Hydrophobic Side Chain – Aliphatic
Name	3-Letter Symbol	1-Letter Symbol	Formula	Molecular Weight	Isoelectric Point	Structure
Alanine	ALA	A	C3H7N1O2	89.09	6.00
Isoleucine	ILE	I	C6H13N1O2	131.17	5.94
Leucine	LEU	L	C6H13N1O2	131.17	5.98
Valine	VAL	V	C5H11N1O2	117.15	5.96

Amino Acids with Hydrophobic Side Chain – Aromatic
Name	3-Letter Symbol	1-Letter Symbol	Formula	Molecular Weight	Isoelectric Point	Structure
Phenylalanine	PHE	F	C9H11N1O2	165.19	5.48
Tryptophan	TRP	W	C11H12N2O2	204.23	5.89
Tyrosine	TYR	Y	C9H11N1O3	181.19	5.66

Amino Acids with Neutral Side Chain
Name	3-Letter Symbol	1-Letter Symbol	Formula	Molecular Weight	Isoelectric Point	Structure
Asparagine	ASN	N	C4H8N2O3	132.12	5.41
Cysteine	CYS	C	C3H7N1O2S1	121.16	5.02
Glutamine	GLN	Q	C5H10N2O3	146.15	5.65
Methionine	MET	M	C5H11N1O2S1	149.21	5.74
Serine	SER	S	C3H7N1O3	105.09	5.68
Threonine	THR	T	C4H9N1O3	119.12	5.64

Amino Acids with Positive Charged Side Chain – Basic
Name	3-Letter Symbol	1-Letter Symbol	Formula	Molecular Weight	Isoelectric Point	Structure
Arginine	ARG	R	C6H14N4O2	174.2	11.15
Histidine	HIS	H	C6H9N3O2	155.16	7.47
Lysine	LYS	K	C6H14N2O2	146.19	9.59

Amino Acids with Negative Charged Side Chain – Acidic
Name	3-Letter Symbol	1-Letter Symbol	Formula	Molecular Weight	Isoelectric Point	Structure
Aspartic Acid	ASP	D	C4H7N1O4	133.1	2.77
Glutamic Acid	GLU	E	C5H9N1O4	147.13	3.22

Other Amino Acids
Name	3-Letter Symbol	1-Letter Symbol	Formula	Molecular Weight	Isoelectric Point	Structure
Glycine	GLY	G	C2H5N1O2	75.07	5.97
Proline	PRO	P	C5H9N1O2	115.13	6.30

Non-proteinogenic amino acids chart

In addition to the 20 standard amino acids, thousands of natural and unatural amino acids exist and can be incorporated in peptide chemical syntheses. Contac SB-PEPTIDE for price estimation of custom peptides containing non-standard amino acids. Non standard amino acids contain derivatives of standard amino acids such as pyroglutamate, citruline, methylated arginine, acetylated lysine, phosphorylated serine / threonine / tyrosine, glycosylated asparagine…

Looking for a specific amino acid to be incorporated in a peptide sequence? please contact us.