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Diazirine peptides: incorporation of Photo-Leucine & Photo-Methionine

sb-PEPTIDE already successfully incorporated photo-reactive amino acids into various peptides. Photo-Leucine and photo-Methionine are photo-reactive amino acids containing a diazirine function which allows to perform photoaffinity labeling studies to determine precisely binding sites in a variety of protein-protein interactions (PPI) such as ligand-receptor interactions, ligand-enzyme, protein-protein…

Photo-leucine & photo-methionine

Photo-leucine & photo-methionine

Recently cited:

« Development of Photocrosslinking Probes Based on Huwentoxin-IV to Map the Site of Interaction on Nav1.7. » Cell Chem Biol. 2019. PMID 31732432