α-conotoxin-IMI - Ion Channels and Transporters
α-conotoxin IMI (alpha-conotoxin IMI) is a conopeptide that has been isolated from the venom of the cone snail Conus imperialis. α-conotoxin IMI acts on postsynaptic membranes, and binds onto and inhibits nicotinic acetylcholine receptors (nAChR). α-conotoxin IMI is a selective blocker of α7 homomeric nicotinic acetylcholine receptors (IC50 ~ 200 nM). It has no effect on nAChRs composed of α2/ß2, α3/ß2, α4/ß2, α2/ß4, α3/ß4, or α4/ß4 subunits. α-conotoxins IMI acts independently of voltage value. This toxin is highly active against the neuromuscular receptor in frog.
Technical specification
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Sequence : | H-GCCSDPRCAWRC-NH2 (Cys2-Cys8 ; Cys3-Cys12) |
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MW : | 1351.56 g/mol |
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Purity : | > 95% |
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Counter-Ion : | TFA Salts |
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Delivery format : | Lyophilized |
Price
| Product | Size | Price € | Price $ |
| 08CON011-0.5 mg | 0.5 mg | 215€ | 258$ |
| 08CON011-1 mg | 1 mg | 363€ | 436$ |
If you'd like to learn more about this toxin, visit our product page on our Smartox website—Our sister company specializing in the synthesis of complex toxins.
