ω-Conotoxin-MVIIC – Ion Channels and Transporters

ω-conotoxin MVIIC (omega conotoxin MVIIC) is a conotoxin that has been isolated from the venom of the cone Conus magus. ω-conotoxin MVIIC is a blocker of P/Q (IC50=35 nM) and N-type calcium channels. It inhibits presynaptic Ca2+ channels, including the Ca2+ channels responsible for Ca2+ uptake by rat brain synaptosomes, the P-type Ca2+ channels in cerebellar Purkinje cells, and a significant fraction of ω-conotoxin GVIA-resistant currents in hippocampal CA1 neurons. ω-conotoxin MVIIC also presents an inhibition of ω-conotoxin GVIA-resistant depolarization-induced neurotransmitter release in cerebellar neurons of rats.

Technical specification

	Sequence :	H-CKGKGAPCRKTMYDCCSGSCGRRGKC-NH2 (Cys1-Cys16; Cys8-Cys20; Cys15-Cys26)
	MW :	2749.25 g/mol
	Purity :	> 95%
	Counter-Ion :	TFA Salts
	Delivery format :	Lyophilized

Price

Product	Size	Price €	Price $
08CON002-0.1 mg	0.1 mg	132€	159$
08CON002-0.5 mg	0.5 mg	330€	396$
08CON002-1 mg	1 mg	561€	674$

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