Conantokin-G - Ion Channels and Transporters
Conantokin-G is a conopeptide that has been isolated from the venom of the cone Conus geographus. Conantokin-G selectively inhibits NR2B containing N-methyl-D-aspartate receptors (NMDAR) with a high specificity. Thus, Conantokin-G inhibits in a concentration-dependent manner the Ca2+ influx leading to a neuroprotective effect against NMDA-induced excitotoxicity. Conantokin-G was shown to block NMDA-evoked currents in murine cortical neurons with an IC50 value of around 480 nM.
Technical specification
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Sequence : | H-GEXXLQXNQXLIRXKSN (X=Gla)-NH2 |
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MW : | 2264.23 g/mol |
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Purity : | > 95% |
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Counter-Ion : | TFA Salts |
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Delivery format : | Lyophilized |
Price
| Product | Size | Price € | Price $ |
| 08CON009-0.5 mg mg | 0.5 mg mg | 121€ | 146$ |
| 08CON009-1 mg | 1 mg | 209€ | 251$ |
If you'd like to learn more about this toxin, visit our product page on our Smartox website—Our sister company specializing in the synthesis of complex toxins.
