Cy5-ProTx-II - Ion Channels and Transporters
Cy5-ProTx-II is a fluorescently labeled ProTx-II, a famous Nav1.7 blocker. The wild type ProTx-II blocks Nav1.7 with an IC50 value of around 300 pM, Nav1.2, Nav1.5 and Nav1.6 with IC50 values of 41 nM, 79 nM and 26 nM respectively. The Cy5-ProTx-II version developed by Smartox has potent Nav1.7 blocking activity. It was shown to fully block Nav1.7 at 100 nM concentration
Technical specification
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Sequence : | Cy5-YCQKWMWTCDSERKCCEGMVCRLWCKKKLW-OH (Cys2-Cys16; Cys9-Cys21; Cys15-Cys25) |
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MW : | 3826.65 g/mol |
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Purity : | > 95% |
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Counter-Ion : | TFA Salts |
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Delivery format : | Lyophilized |
Price
| Product | Size | Price € | Price $ |
| PTF002-5 x 0.01 mg | 5 x 0.01 mg | 484€ | 581$ |
If you'd like to learn more about this toxin, visit our product page on our Smartox website—Our sister company specializing in the synthesis of complex toxins.
