Fibrinogen (377-395) Human - Other Categories

Fibrinogen (377-395) Human is derived from Fibrinogen, which is a large plasma glycoprotein with a complex structure, and one of the most abundant proteins in blood. Fibrinogen is important in fibrin clot formation, haemostasis, and inflammatory responses. Increased plasma fibrinogen indicates a proinflammatory state and is a risk factor for vascular inflammatory diseases including hypertension and atherosclerosis. Fibrinogen cleavage products act as inflammatory activators in the pathophysiology of allergic asthma. Fibrinogen (377-395) Human is capable of preventing microglia activation by inhibiting the Mac-1 receptor, which in turn suppresses relapsing paralysis.