Iberiotoxin – Ion Channels and Transporters

Iberiotoxin (IbTx) is a toxin that was originally isolated from Buthus tamulus scorpion venom. Iberiotoxin inhibits selectively the high conductance Ca2+-activated K+ channel (KCa1.1) at nanomolar concentrations (IC50 ~2 nM). This toxin does not affect other types of calcium-dependent or voltage-dependent K+ channels. Iberiotoxin is a valuable tool to study specifically Maxi-K channels.

Technical specification

	Sequence :	pQ-FTDVDCSVSKECWSVCKDLFGVDRGKCMGKKCRCYQ-OH (Cys7-Cys28; Cys13-Cys33; Cys17-Cys35)
	MW :	4230.85 g/mol
	Purity :	> 95%
	Counter-Ion :	TFA Salts
	Delivery format :	Lyophilized

Price

Product	Size	Price €	Price $
12IBX001-0.5 mg	0.5 mg	429€	515$
12IBX001-1 mg	1 mg	605€	726$
12IBX001-5 x 0.01 mg	5 x 0.01 mg	132€	159$

If you’d like to learn more about this toxin, visit our product page on our Smartox website—Our sister company specializing in the synthesis of complex toxins.

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