TPL-2tide - Other Categories

Tumour progression locus 2 (TPL2) is a mitogen-activated protein kinase kinase (MAP3 K) and is critical for the production of tumour necrosis factor alpha (TNFalpha) in innate immune responses and a potential anti-inflammatory drug target. TPL-2 forms a complex with NF-KB1, p105 and ABIN-2. TPL-2tide is phosphorylated by TPL-2, making TPL-2tide a useful tool for use in kinases assays.