Waglerin-1-FAM - Ion Channels and Transporters
Waglerin-1 (Wtx-1) is a peptide originally isolated from the venom of the Wagler’s pit viper (Trimeresurus wagleri). This 22 amino-acid peptide is a competitive antagonist of adult muscle nicotinic acetylcholine receptors. Waglerin-1 binds selectively to epsilon subunit of nAChR. Some studies have demonstrated that Waglerin-1 has an effect on ionotropic GABA receptors. It may potentiate or depress I(GABA) depending on the neurons. Some derivatives of Waglerin-1 are currently used in cosmetics to reduce wrinkles. The fluorescent derivative Waglerin-1-FAM can be use to explore the expression and function of the adult nAChR subtypes.
Technical specification
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Sequence : | H-(FAM)GGKPDLRPCHPPCHYIPRPKPR-OH (Cys9-Cys13) |
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MW : | 2878.26 g/mol |
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Purity : | > 95% |
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Counter-Ion : | TFA Salts |
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Delivery format : | Lyophilized |
Price
| Product | Size | Price € | Price $ |
| WAG002-0.1 mg | 0.1 mg | 198€ | 238$ |
| WAG002-0.5 mg | 0.5 mg | 616€ | 740$ |
| WAG002-1 mg | 1 mg | 1045€ | 1254$ |
If you'd like to learn more about this toxin, visit our product page on our Smartox website—Our sister company specializing in the synthesis of complex toxins.
