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VGB4

VGB4 – Other Categories Antagonist peptide of VEGF-A and VEGF-B reproducing two binding regions of VEGF-B (loop 1 and loop3) linked together by a receptor binding region of VEGF-A (loop3). Binds to both VEGFR1 and VEGFR2 and inhibits VEGF-A driven proliferation,...

Fas blocking peptide

Fas blocking peptide – Other Categories Blocks Fas-FasL interaction, and in the Neuro2a cell model of ischemia protects against ischemic stroke-induced neuronal cell death by binding to Fas expressing cells and rescuing them from Fas mediated apoptosis.  ...

P12 amide

P12 amide – Other Categories Interactions between ECM proteins and growth factors were only thought to concentrate growth factors and to enhance their multimerisation for signalling. However, recent studies indicate that binding of growth factors to ECM proteins...

M2-Influenza

M2-Influenza – Other Categories Influenza virus budding from infected cells requires membrane remodelling, is a multistep process with many proteins involved. Therefore there are numerous stages and proteins that could be antiviral targets if the mechanism can...

HiBiT tag

HiBiT tag – Other Categories NanoLuc (Nluc) is an engineered luciferase protein which was developed from the luciferase of deep-sea shrimp (Oplophorus gracilirostris). This luciferase protein is considerably smaller than firefly or Renilla luciferase yet has...