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ARF peptide

ARF peptide – Cancer Peptides ARF peptide, is the alternative frame (ARF) tumour suppressor protein which is expressed on the occurrence of oncogenic stimuli. It functions to prevent abnormal cell proliferation through inhibiting the p53 ubiquitin ligase protein...

GRGD-acid

GRGD-acid – Cancer Peptides GRGD-acid is a cell adhesive peptide containing the RGD motif. This enables it the ability to increase cell adhesion and rates of cell growth, differentiation and proliferation. When immobilised onto a Poly(etheretherketone) (PEEK)...

HIF-1 α (556-574)

HIF-1 α (556-574) – Cancer Peptides HIF-1 alpha (556-574) is derived from hypoxia-inducible factor 1-alpha (HIF-1 alpha), a subunit of the heterodimeric transcription factor HIF-1 and is responsible for maintaining oxygen homeostasis. HIF-1 alpha is expressed...

dodecapeptide AR71

dodecapeptide AR71 – Cancer Peptides The dodecapeptide AR71 prevents melanoma inhibitory activity (MIA) dimerisation and hence inhibits (MIA). It therefore has the potential to be used as a therapeutic in melanoma.   Technical specification Sequence :...

BIM 187

BIM 187 – Cancer Peptides Bombesin/GRP receptor agonist derived from the pro-apoptotic protein BIM, which is a member of the BCL-2 family proteins and activates the BAX and BAK proteins to promote apoptosis. The process of apoptosis can be activated by the...