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GRGD-acid

GRGD-acid – Cancer Peptides GRGD-acid is a cell adhesive peptide containing the RGD motif. This enables it the ability to increase cell adhesion and rates of cell growth, differentiation and proliferation. When immobilised onto a Poly(etheretherketone) (PEEK)...

HIF-1 α (556-574)

HIF-1 α (556-574) – Cancer Peptides HIF-1 alpha (556-574) is derived from hypoxia-inducible factor 1-alpha (HIF-1 alpha), a subunit of the heterodimeric transcription factor HIF-1 and is responsible for maintaining oxygen homeostasis. HIF-1 alpha is expressed...

dodecapeptide AR71

dodecapeptide AR71 – Cancer Peptides The dodecapeptide AR71 prevents melanoma inhibitory activity (MIA) dimerisation and hence inhibits (MIA). It therefore has the potential to be used as a therapeutic in melanoma.   Technical specification Sequence :...

BIM 187

BIM 187 – Cancer Peptides Bombesin/GRP receptor agonist derived from the pro-apoptotic protein BIM, which is a member of the BCL-2 family proteins and activates the BAX and BAK proteins to promote apoptosis. The process of apoptosis can be activated by the...

Proapoptotic Peptide KLA

Proapoptotic Peptide KLA – Cancer Peptides Proapoptotic peptide KLA is a cationic amphipathic peptide that disrupts the mitochondrial membrane. Proapoptotic peptide KLA cannot of its own accord cross eukaryotic cell membranes and is therefore not toxic to the...