Acetyl Decapeptide-3 / Rejuline

Signal peptide for skin regeneration and ECM stimulation

Acetyl Decapeptide-3 (trade name Rejuline®) is a 10-amino acid acetylated signal peptide that stimulates extracellular matrix (ECM) remodeling and activates the skin's natural UV-damage response. By promoting fibroblast activity and collagen synthesis, it visibly reduces fine lines and wrinkles while improving overall skin texture. Suitable for anti-aging serums, post-UV repair formulations, and premium skincare actives.

Main characteristics

Acetyl Decapeptide-3 mimics the signaling activity of growth factors, stimulating fibroblast metabolism and ECM production without requiring biological expression systems. Its acetylated N-terminus enhances stability against proteolytic degradation, ensuring a longer active life in cosmetic formulations. Compatible with standard aqueous formulations, emulsions, and serum bases. Produced via solid-phase peptide synthesis (SPPS) to ≥95% purity confirmed by HPLC and MS.

Applications

Anti-aging serums and face creams targeting fine lines and wrinkles
Post-UV exposure repair formulations
ECM-stimulating actives in premium skincare
Research applications in skin biology and fibroblast activity studies

Technical specification

	Sequency :	Ac-YRSRKYTSWY-NH2
	INCI name	Acetyl Decapeptide-3
	MW :	1449.71 g/mol
	Purity :	> 95%
	Counter-Ion :	TFA Salts
	Delivery format :	Lyophilized
	CAS number :	935288-50-9

TFA removal service available (acetate or HCl exchange)

Price

Product	Size	Price €	Price $
SB348-20mg	20 mg	288.02	345.62
SB348-50mg	50 mg	432.02	518.43
SB348-100mg	100 mg	576.03	691.24
SB348-500mg	500 mg	1123.26	1347.92

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Custom Cosmetic Peptides Services

If your target is not listed, we offer custom Cosmetic Peptides design and synthesis. Whether you require sequence optimization, specific modifications, or larger production quantities, our team can support your project. Submit your project details and we will provide a personalized proposal.

Analytical Documentation Included
A Certificate of Analysis (CoA), MS analysis, and HPLC purity report are provided with every batch.

Research Use Only
For research and laboratory use only. Not for human consumption or therapeutic use.

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