Pentapeptide-31

Signal pentapeptide for skin ECM renewal and regenerative anti-aging

Pentapeptide-31 is a synthetic signal pentapeptide that supports skin regeneration and ECM structural renewal by activating fibroblast and keratinocyte signaling pathways. It promotes the synthesis of structural ECM components and accelerates skin cell turnover, improving overall skin quality. Suitable for anti-aging, resurfacing, and regenerative formulations where skin renewal and ECM remodeling are primary objectives.

Main characteristics

Pentapeptide-31 provides a clean, synthetic signal peptide option for ECM renewal with a straightforward AGELS sequence. Its small molecular weight facilitates dermal penetration. Compatible with most anti-aging serum and cream bases. Stable at pH 5.0–7.5. Produced via SPPS to ≥95% purity (HPLC + MS).

Applications

Anti-aging skin renewal serums and treatments
Formulations targeting skin texture improvement
ombination peptide anti-aging systems
Post-peel and regenerative skincare
Research in fibroblast and keratinocyte activation via signal pentapeptides

Technical specification

	Sequency :	H-AGELS-NH2
	INCI name	Pentapeptide-31
	MW :	474.51 g/mol
	Purity :	> 95%
	Counter-Ion :	TFA Salts
	Delivery format :	Lyophilized
	CAS number :	1232137-75-5

TFA removal service available (acetate or HCl exchange)

Price

Product	Size	Price €	Price $
SB379-20mg	20 mg	351.82	422.19
SB379-50mg	50 mg	527.73	633.28
SB379-100mg	100 mg	703.64	844.37
SB379-500mg	500 mg	1372.10	1646.52

For more information about Cosmetic Peptides, please visit our dedicated page.

Explore our Cosmetic Catalog products. Click HERE to discover additional reference compounds.

Custom Cosmetic Peptides Services

If your target is not listed, we offer custom Cosmetic Peptides design and synthesis. Whether you require sequence optimization, specific modifications, or larger production quantities, our team can support your project. Submit your project details and we will provide a personalized proposal.

Analytical Documentation Included
A Certificate of Analysis (CoA), MS analysis, and HPLC purity report are provided with every batch.

Research Use Only
For research and laboratory use only. Not for human consumption or therapeutic use.

Submit a Custom Request

Get a Quote