Tetrapeptide-30

Reduces UV-induced pigmentation and melanin production

Tetrapeptide-30 is a dual-function tetrapeptide with concurrent anti-inflammatory and mild depigmenting activity. It reduces pro-inflammatory cytokine production in skin cells while modulating melanin production pathways, making it uniquely suited for formulations that address both skin sensitivity and uneven skin tone simultaneously. Particularly effective for post-inflammatory hyperpigmentation (PIH), where both inflammation control and melanogenesis inhibition are simultaneously required.

Main characteristics

Tetrapeptide-30's dual mechanism, anti-inflammatory plus depigmenting, makes it one of the most versatile brightening actives for sensitive skin, addressing the common scenario where hyperpigmentation is driven or exacerbated by inflammation (PIH, melasma, acne-related dark spots). Compatible with niacinamide, vitamin C, and other brightening actives for synergistic systems. Stable at pH 5.0–7.5. Produced via SPPS to ≥95% purity (HPLC + MS).

Applications

Brightening serums for sensitive skin
Post-inflammatory hyperpigmentation (PIH) treatment formulations
Anti-redness + brightening combination products
Melasma treatment in sensitive skin types
Research in dual anti-inflammatory/depigmenting peptide mechanisms

Technical specification

	Sequency :	H-PKEK-OH
	INCI name	Tetrapeptide-30
	MW :	500.58 g/mol
	Purity :	> 95%
	Counter-Ion :	TFA Salts
	Delivery format :	Lyophilized
	CAS number :	1036207-61-0

TFA removal service available (acetate or HCl exchange)

Price

Product	Size	Price €	Price $
SB382-20mg	20 mg	351.82	422.19
SB382-50mg	50 mg	527.73	633.28
SB382-100mg	100 mg	703.64	844.37
SB382-500mg	500 mg	1372.10	1646.52

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Custom Cosmetic Peptides Services

If your target is not listed, we offer custom Cosmetic Peptides design and synthesis. Whether you require sequence optimization, specific modifications, or larger production quantities, our team can support your project. Submit your project details and we will provide a personalized proposal.

Analytical Documentation Included
A Certificate of Analysis (CoA), MS analysis, and HPLC purity report are provided with every batch.

Research Use Only
For research and laboratory use only. Not for human consumption or therapeutic use.

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