Palmitoyl Tripeptide-1

Stimulates collagen synthesis and skin repair

Palmitoyl Tripeptide-1 (Pal-GHK) is the lipidated derivative of the naturally occurring GHK tripeptide, with a palmitoyl chain that enhances dermal penetration through the lipid-rich stratum corneum. It stimulates fibroblast production of Collagen I, III, and Fibronectin via the matrikine signaling pathway. In the widely used Matrixyl 3000® complex, it is paired with Palmitoyl Tetrapeptide-7 (Rigin) to provide complementary collagen-building and anti-inflammatory actions.

Main characteristics

Palmitoyl Tripeptide-1's matrikine activity is based on the same endogenous GHK signaling that naturally occurs during collagen matrix remodeling. The palmitoyl group makes the ingredient formulation-versatile: it is compatible with both aqueous and lipid-based systems. As a core component of Matrixyl 3000, one of the most commercially proven anti-aging peptide complexes, its efficacy is supported by substantial clinical evidence. Produced via SPPS to ≥95% purity (HPLC + MS).

Applications

Anti-aging serums and creams
Collagen-boosting concentrates and ampoules
Oil-based and emulsion anti-aging formulations
Combination products with Palmitoyl Tetrapeptide-7 for full Matrixyl 3000 complex
Research in matrikine signaling and GHK biology

Technical specification

	Sequency :	Pal-GHK-OH
	INCI name	Palmitoyl Tripeptide-1
	MW :	578.79 g/mol
	Purity :	> 95%
	Counter-Ion :	TFA Salts
	Delivery format :	Lyophilized
	CAS number :	147732-56-7

TFA removal service available (acetate or HCl exchange)

Price

Product	Size	Price €	Price $
SB374-20mg	20 mg	351.82	422.19
SB374-50mg	50 mg	527.73	633.28
SB374-100mg	100 mg	703.64	844.37
SB374-500mg	500 mg	1372.10	1646.52

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Custom Cosmetic Peptides Services

If your target is not listed, we offer custom Cosmetic Peptides design and synthesis. Whether you require sequence optimization, specific modifications, or larger production quantities, our team can support your project. Submit your project details and we will provide a personalized proposal.

Analytical Documentation Included
A Certificate of Analysis (CoA), MS analysis, and HPLC purity report are provided with every batch.

Research Use Only
For research and laboratory use only. Not for human consumption or therapeutic use.

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