Palmitoyl Tripeptide-38

Stimulates collagen, hyaluronic acid and extracellular matrix components

Palmitoyl Tripeptide-38 is a synthetic matrikine-mimetic lipopeptide designed to stimulate the production of key extracellular matrix (ECM) components, including collagen, hyaluronic acid, and other structural proteins involved in maintaining skin firmness and elasticity. By acting across multiple skin layers, it helps improve skin smoothness, hydration, and the appearance of wrinkles.

Main characteristics

Palmitoyl Tripeptide-38 stimulates the production of six key extracellular matrix (ECM) components, including collagens, fibronectin, laminin, and hyaluronic acid, combining collagen-supporting and hydration-enhancing benefits within a single molecule. This broad-spectrum ECM activation makes it one of the most advanced signal peptides used in modern anti-aging skincare formulations. Stable at pH 4.5–7.5. Compatible with standard serum and cream bases. Produced via SPPS to ≥95% purity (HPLC + MS).

Applications

Premium anti-aging serums and creams
Multi-target ECM remodeling concentrates
Anti-wrinkle firming and hydrating combined treatments
Research in multi-target ECM stimulation and matrikine-beyond signaling

Technical specification

	Sequency :	Pal-KMK-OH
	INCI name	Palmitoyl Tripeptide-38
	MW :	643.96 g/mol
	Purity :	> 95%
	Counter-Ion :	TFA Salts
	Delivery format :	Lyophilized
	CAS number :	1447824-23-8

TFA removal service available (acetate or HCl exchange)

Price

Product	Size	Price €	Price $
SB377-20mg	20 mg	351.82	422.19
SB377-50mg	50 mg	527.73	633.28
SB377-100mg	100 mg	703.64	844.37
SB377-500mg	500 mg	1372.10	1646.52

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Custom Cosmetic Peptides Services

If your target is not listed, we offer custom Cosmetic Peptides design and synthesis. Whether you require sequence optimization, specific modifications, or larger production quantities, our team can support your project. Submit your project details and we will provide a personalized proposal.

Analytical Documentation Included
A Certificate of Analysis (CoA), MS analysis, and HPLC purity report are provided with every batch.

Research Use Only
For research and laboratory use only. Not for human consumption or therapeutic use.

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