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IRS-1 substrate

IRS-1 substrate – Growth Factors and Cytokines Insulin receptor (IR) substrate 1 (IRS-1) peptide is a highly selective substrate for certain kinase sub-families- such as receptor tyrosine kinases (which includes IR). IRS-1 is also a very good substrate for the...

SRC Substrate Peptide

SRC Substrate Peptide – Growth Factors and Cytokines Src is a member of the Src family tyrosine kinases (SFKs), a large cytosolic, non-receptor, kinase family that controls multiple signalling pathways in animal cells. SFKs play key roles in cell morphology and...

HSP70/DnaK Substrate Peptide

HSP70/DnaK Substrate Peptide – Growth Factors and Cytokines Model substrate peptide for heat shock protein 70 (HSP70)/ Chaperone protein DnaK. Binds to the substrate binding domain of DnaK and is used in co-crystallisation assays. DnaK is the most well studied...

N-methylated ERAP1substrate

N-methylated ERAP1substrate – Growth Factors and Cytokines Non-hydrolysable ERAP1 substrate. An optimized ERAP1 substrate with N-methylation of the first amide bond to prevent its degradation by ERAP1. Endoplasmic reticulum aminopeptidase 1 and 2 (ERAP1 and...

CSK substrate

CSK substrate – Growth Factors and Cytokines Substrate peptide for C-terminal Src kinase (Csk) for use in kinase assays. Csk is a cytosolic tyrosine kinase that is closely related to the kinase Src and is a well-known negative regulator of Src family kinases....