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SAMS peptide

SAMS peptide – Growth Factors and Cytokines SAMS peptide was originally designed as a selective substrate for mammalian 5′ adenosine monophosphate-activated protein kinase (AMPK) for use in kinase assays. However it is also able to be phosphorylated by the...

P7

P7 – GPCR Modulators G protein-coupled receptor 56 (GPR56/ ADGRG1) is a novel and evolutionarily conserved regulator of peripheral nerve development and function, with important implications for human health and disease. During Schwann cell (SC) development,...

PAR-2 receptor agonist

PAR-2 receptor agonist – GPCR Modulators Protease activated receptors (PARs) are a distinctive four-member family of seven transmembrane G protein-coupled receptors (GPCRs) widely expressed in inflammatory cells. PARs are cleaved by certain serine proteases to...

PAR-2 Agonist amide

PAR-2 Agonist amide – GPCR Modulators Thrombin receptor inhibitory peptide (TRIP). Thrombin activates members of the PAR family of receptors to initiate a variety of signalling pathways. Protease activated receptors (PARs) are a distinctive four-member family of...

PAR-1 Antagonist

PAR-1 Antagonist – GPCR Modulators YFLLRNP works as a partial PAR-1 agonist that induces platelet shape change without calcium mobilization via the galpha12/13 signalling cascade. Full activation of platelets is only achieved at higher concentrations. YFLLRNP...